Palo Alto Medical Foundation Newsroom

NIH Awards $3M Grant to PAMF Researchers to Study Physical Activity Effects on Type 2 Diabetes

Researchers at the Palo Alto Medical Foundation Research Institute (PAMFRI) have received a five-year, $3 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study physical activity among individuals with type 2 diabetes.

Type 2 diabetes is the most common form of diabetes and affects 25.8 million people in the United States – nearly one in 10 Americans.  If current trends continue, it is estimated that one in three American adults will have diabetes by the year 2050.

Lifestyle changes, such as diet and exercise, are an essential part of maintaining a healthy lifestyle, and preventing and controlling diabetes. The current American Diabetes Association (ADA) guidelines recommend that individuals with type 2 diabetes engage in at least 150 minutes of moderate-intensity aerobic physical activity every week, as well as strength training three times per week. Current studies show that nearly 70 percent of individuals with type 2 diabetes do not exercise at recommended levels – or at all.

“There is clearly a need to extend physical activity interventions into the clinical setting,” says Latha Palaniappan, M.D., associate investigator at the Palo Alto Medical Foundation Research Institute and principal investigator for this study.

The Initiate and Maintain Physical Activity in Clinics (IMPACT) study will examine an innovative structured group exercise program within the clinic.

“This study will help patients with diabetes get active and stay active.  We have an important opportunity to improve the care of diabetes nationwide, with innovative science here at the Palo Alto Medical Foundation,” said Dr. Palaniappan.

The IMPACT Study will fill an important research gap by making physical activity an essential part of type 2 diabetes management, establishing it within a health care setting and empowering patients to initiate and maintain physical activity recommendations long-term.

This study, starting in January 2014, will enroll approximately 300 patients with type 2 diabetes.  Adults interested in participating should contact: for more information.